Pharmacology

Artificial Sweeteners do NOT affect Appetite, Energy Intake or Food Choices Versus Water *

Posted: May 13 in Pharmacology, Research by

A recent study published in Appetite, shows that when compared to water, artificial sweeteners (low calorie sweeteners) (LCS) do not affect appetite, energy intake or food choices.    For several years, it has been believed commonly (but falsely), that the replacement of sugar by LCS results in several maladaptive physiologic changes including uncoupling of the LCS […]

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Does Phentermine cause heart disease? *

Posted: May 10 in Pharmacology, Research by

New study affirms long term safety. It has been well documented that lifestyle modifications can assist many in their weight loss journey. Lifestyle interventions include dietary modifications and exercise as a root change.  Why are we hesitant to using pharmacotherapies to treat obesity, especially long term?    Using Phentermine long term has remained a debated topic […]

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Obesity Medication Update *

Posted: Jan 24 in Pharmacology by

Anti-obesity medications are FDA approved for patients who have a BMI over 30 and for patients who have a BMI over 27 if they also have a weight related medical condition, like high blood pressure, high cholesterol, type 2 diabetes mellitus or sleep apnea. I also use medication if a patient has obesity based on body fat percentage, which is generally accepted to be >32% for women and >25% for men. [Read more]

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Metformin Underused in Patients With Prediabetes. *

Posted: Jan 24 in Pharmacology, Research by

One of the most common diseases treated in our obese/overweight populations is Diabetes. Why are we hesitant to using Metformin early? Early use of Metformin has been a topic for years with the US Diabetes Prevention Program (DPP) results and the follow-up DPP Outcomes Study (DPPOS). Both of these studies have shown the decrease in the prevalence of diabetes developing with the addition of metformin. Combined with lifestyle modifications, results were even better. [Read more]

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Is phentermine addicting and is long-term use safe? *

Posted: Jan 24 in Pharmacology, Research by

Phentermine was approved for use in 1959 and for a period of 12 weeks. As obesity has been identified as a chronic disease, the long term use of phentermine has become mainstream amongst physicians who practice full-time obesity medicine. 97% of obesity medicine specialists indicate phentermine is their drug of choice among the current medication options available. Reasons for this include efficacy, safety, tolerability, low cost and low addiction potential. Despite this, concerns regarding safety and addiction potential have continued to limit the use by some physicians. [Read more]

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