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NASH Rapidly Overtaking Hepatitis C as a Cause of Liver Cancer
By: Scottsdale Weight Loss Center
Published: January 24, 2019
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Comments on article NASH rapidly overtaking hepatitis C as cause of liver cancer
BY BIANCA NOGRADY FROM THE JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGY
I recently read this article and it struck me as something we should be paying more attention to.
Definitions
“NAFLD” describes hepatic steatosis with hepatocyte fat accumulation in a liver without inflammation.
“NASH” describes fat accumulation, hepatic inflammation and hepatocyte injury with or without fibrosis or cirrhosis.
Facts from the Article:
- NAFLD develops in the absence of significant alcohol abuse, hereditary disorders or causative medications and is often associated with obesity.
- The prevalence of NAFLD in the US is estimated to be 30-46% and is the most common form of liver disease in Western countries.
- The clinical predictors of advanced fibrosis in NAFLD include: hypertension, diabetes mellitus and visceral obesity.
- In 2015 NASH was the number one indication for liver transplantation in patients aged <50 years (surpassing HCV infection)!
- Weight loss of 3% can decrease hepatic steatosis (NAFLD), 5% can decrease inflammation (NASH), 7% can resolve NASH and 10% can regress fibrosis!
As Obesity Medicine physicians, we see patients with NAFLD/NASH every day. I have seen many patients with elevations in LFTs that normalize within several months of treatment. Not to mention the resolution of hypertension and DM2 as risk factors for NAFLD/NASH.
Nick
Nick's Story
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Lost 44.5 lbs
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I will always have my relationship with Scottsdale Weight Loss Center. They truly helped me change my life forever." Read More
Lauren
Lost 60 lbs
"Dr. Ziltzer and everyone who I have come in contact with at the Scottsdale Weight Loss office have been so encouraging and I look forward to seeing them each week. It is now a year and 2 months later since I started. I am down 60 lbs., which is the average amount a 9-year-old weighs, it is crazy to think I lost a whole person! I feel amazing, I hit my goal weight in November 2021 just before Thanksgiving. Nothing on my body hurts anymore..." Read More
Chuck
Lost 66 lbs
"The best thing I did was call the Scottsdale Weight Loss Center. I have a lot more energy, I'm not hungry, and it feels great.
You can take it from me that this is a program that produces results. The staff is always positive, supportive, and never judgmental.
Your visits always result in positive reinforcement, no matter if you had a good week or a bad week." Read More
Emily
Lost 101 lbs
"Here I am at the lowest I have been since high school weighing in at 155lbs. I have lost 101 lbs, BMI of 39 when I started, to 21.6, and of course at body fat % of 47.1 to 26.5%. I told myself by my 30th birthday I wanted to be confident in the way I look and I owe it all to SWLC. The entire staff is so welcoming and they are rooting for you just as much as you are rooting for yourself...." Read More
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Meet Our Team
Robert Ziltzer, MD, FACP, FAAP, FOMA
Obesity Medicine Certified Physician
Diana Bone, FNP-C
Specializing in Obesity Medicine
Craig Primack, MD, FACP, FAAP, MFOMA
Obesity Medicine Certified Physician
Kristen Ash, FNP-C, FNP-BC
Nurse Practitioner
Alicia Earley, FNP-C
Family Nurse Practitioner
